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Dimitrow PP, Rajtar-Salwa R (2016): Obstructive Form of Hypertrophic Cardiomyopathy-Left Ventricular Outflow Tract Gradient: Novel Methods of Provocation, Monitoring of Biomarkers, and Recent Advances in the Treatment

And and least in those who stay on the treatment forever So what happens when you discontinue the drugs

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Clinically studied to influence thousands of genes, this molecule promotes regeneration, repair, and protective pathways across multiple tissues including skin, connective tissue, hair follicles, lungs, bones, and the nervous system

This framing explicitly links stroke pathophysiology to the buffer concept and clarifies why benefits may be greatest in penumbral and reperfusion contexts rather than the infarct core