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Under this frame, it was observed that the association between lead exposure and ALS risk may correlate with particular GSTP1 gene polymorphisms 66

To test this possibility, we established and performed isotope labeled glutathione (GSH-(glycine- 13 C 2 , 15 N)) uptake assays using mitochondria isolated from SLC25A39 knockout cells and those expressing an SLC25A39 cDNA (Extended Data Fig

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Mitochondria contain multiple copies of their own genome, mitochondrial DNA (mtDNA), which encodes for 13 polypeptides of the OXPHOS and respiratory chain, as well as two ribosomal RNAs and 22 transfer RNAs necessary for translation of polypeptides inside mitochondria

Group 1 as a control group) is given standard feed, and group 2 as ginger honey as much as 42mg/20g BW is given by oral sonde and standard feed for 14 days