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doi: 10.2337/dc15-1025 Summary Keywords obesity, adiposity, insulin resistance, overweight, weight loss Citation Resnick O, Bril F and Beauchamp G (2025) Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer

The RELATE study was a real-world retrospective database study of 1926 adults with T2D, which utilized linked data from IQVIAs Longitudinal Prescription Claims, Professional Fee Claims and AEMR in the USA

Consistent with these in vivo findings, ex vivo stimulation of lamina propria immune cells with butyrate increased IL-22 levels in IL-22RA1 (f/f) mice, whereas LP cells from IL-22RA1 Vil KO mice showed only minimal induction (Supplementary Fig

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Retatrutide is the first compound to engage all three receptors simultaneously, creating what researchers describe as a comprehensive metabolic intervention