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Consistent with this, mice homozygous for a spontaneous null mutation of the gene showed no defects in growth or DNA replication (Rogers et al., 2004), and mice zygotically homozygous-null for either the gene encoding cytosolic Trx1 (Matsui et al., 1996) or the gene encoding cytosolic TrxR1 (Bondareva et al., 2007

Starting from D17 cultured cells were maintained in neurobasal media without neurotrophins

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Next to biochemical differences between the defensin subgroups, there are crucial varieties regarding their biology

However, BS remains invasive and is not readily scalable at the population level