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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily licensed for the management of type 2 diabetes mellitus and, in specific cases, for weight management

Repeated freeze-thaw cycles can compromise peptide integrity

[ Acknowledgements The work was partially supported by the Italian Ministry of University (MIUR)

The mean duration of follow-up in the studies was 2.7 years

In this study, we have investigated the effects of moderate exercise (1 h/day, 5 days a week for 60 days) on mitochondrial, metabolic, and oxidative stress-related changes in the liver and kidney of type 2 diabetic Goto-Kakizaki (GK) rats