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Description

An imbalance in the gut microbial community is recognized as driver in the pathogenesis of a spectrum of hepatic conditions, such as NAFLD, ALD, and HCC

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Elevated calcitonin (above 50 pg/mL) is a disqualifying finding

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Other monitored potential side effects include Nausea Vomiting Diarrhea Constipation Decreased appetite Transient increases in heart rate Gallbladder-related events (e.g., cholelithiasis) Elevated pancreatic enzymes These side effects typically diminish over time with continued treatment and appropriate dose titration

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doi: 10.1136/gut.2010.228908 165 MaCStorerCEChandranULaFramboiseWAPetroskoPFrankMet al

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