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The particle size and method of administration are significant factors in determining whether a drug reaches the alveolus and, therefore, the systemic circulation, or whether it only reaches the upper airways

Thus, being able to measure all forms of GSH in one well significantly reduced the sample volume required for our experiment and mitigated inter-plate variation as a confound in data analysis

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doi: 10.1124/dmd.109.030197 10 AsadollahiA.SarirH.OmidiA.TorbatiM