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Patients should be counseled to report immediately any new or worsening visual symptoms including: Blurred or distorted central vision Difficulty reading or recognizing faces Straight lines appearing wavy (metamorphopsia) Dark or empty areas in central vision Sudden vision loss or floaters Home monitoring with an Amsler grid can help patients with AMD detect subtle changes in central vision between appointments, as recommended by the NEI and AAO

Given that most participants experienced obesity since puberty, and semaglutide is approved in adolescents over 12, similar research in a youth population may be beneficial

Some may increase sensitivity, while others reduce effectiveness

doi:10.1016/j.crbeha.2021.100036 Astrup A