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Kenya is experiencing heavy rains that have disrupted normal business across the East African country, resulting in the loss of more than 38 lives and the destruction of property.(Photo: Xinhua) Residents are trapped after heavy rains in the Mathare slums of Nairobi, Kenya, on April 24, 2024

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When autophagy initiates, LC3-I undergoes a critical modification involving conjugation to phosphatidylethanolamine (PE), converting it to LC3-II, which then localizes to the lipid membrane of nascent autophagosomes (Amaravadi et al., 2011)