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Functional enrichment indicated strong activation of iron transport and lipid peroxidation pathways, but weak engagement of glutathione metabolism, suggesting selective vulnerability to iron-driven oxidative stress
A patients response may depend on: Starting weight Insulin resistance Appetite patterns Hormone changes Sleep quality Stress levels Muscle mass Nutrition habits Medication tolerance Dose progression Follow-up consistency Some patients begin comparing medications after a plateau, when semaglutide or tirzepatide results may slow over time and the treatment plan needs to be reassessed
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When people stop taking these medications, most of the weight comes back
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