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Topiramate possesses more than one mechanism of action, which may explain why it can be effective in patients with various seizures that are refractory to other agents

Determination of intracellular reactive oxygen species (ROS) levels Total intracellular ROS levels were determined using a ROS assay kit (cat

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IGF-1R and mTOR blockade: novel resistance mechanisms and synergistic drug combinations for Ewing sarcoma