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Inherited errors in mechanisms regulating purine metabolism (principally X-linked deficiency of hypoxanthine guanine phosphoribosyl transferase (HPRT) activity and superactivity of phosphoribosyl pyrophosphate (PRPP) synthetase account for a very small fraction of patients with uric acid overproduction

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Summary of the Contrave Subsection (Mini-List) Targets cravings and emotional eating patterns Modulates dopamine, norepinephrine, and reward circuits Useful for patients with stress driven or habit driven eating Requires careful titration and monitoring Provides a valuable non stimulant, non injectable treatment option Why We Do Not Use Compounded Weight Loss Medications Compounded versions of semaglutide, tirzepatide, or similar medications have become widely advertised by online clinics, medspas, and cash-pay weight loss programs

2020;36((Suppl