Medicine (Baltimore) 84:137146
The maintenance of nitrogen balance depends significantly on this role during times of metabolic stress
However, clinical outcomes remained variable and were limited by heterogeneity in UV protocols, surface systems, endpoints, and follow-up duration
However, when comparing the injury after an overdose, only mice generally develop a similar degree of liver injury as observed in humans [123, 124]
Additionally, studies have demonstrated that removing the insulin receptor in mice decreases blood glucose levels in response to IGF-1, indicating that IGF-1 can compensate for insulin's role in glucose metabolism to some extent (Clemmons, 2004)