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In the UK, medical guidelines and manufacturers state that GLP-1 medications should not be used if you have: A personal or family history of Medullary Thyroid Cancer (MTC)

Hormonal fluctuations throughout the menstrual cycle can affect how side effects manifest, with some women reporting that nausea is more pronounced during certain phases of their cycle

[1] [2] Additionally, the immediate systemic exposure might provoke more severe gastrointestinal distress than typically experienced with subcutaneous administration

These groups do not represent contraindications for GLP-1RA therapy

You give Ozempic as a once-weekly subcutaneous injection after a healthcare professional teaches you how to inject it