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Body weight Larger bodies distribute semaglutide across more tissue

The distinction matters for metabolic health: tirzepatide appears to improve insulin sensitivity more robustly than semaglutide in some trials, particularly in patients with prediabetes or type 2 diabetes

Enhances red blood cell production

When the body is exposed to mycotoxins, it uses up large amounts of glutathione to try and neutralize and eliminate them, leading to a rapid depletion of glutathione levels

Recent postmarketing data (reports from people whove used the medication since it became available for use) has also identified more serious complications , including ileus (a type of intestinal blockage) and severe constipation leading to fecal impaction