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However, research published in the Annals of Internal Medicine found an important nuance: longer-acting GLP-1 receptor agonists (which includes both tirzepatide and once-weekly semaglutide) were actually associated with lower GERD risk than shorter-acting versions like liraglutide
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Liraglutide: A review of the first once-daily GLP-1 receptor agonist
It also avoids the intense hunger stimulation characteristic of GHRP-6
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