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3 Overview of ferroptosis 3.1 Evolutionary insights into ferroptosis The conceptual foundation of ferroptosis was laid in 2003 when Dolma et al

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Increasing the expression of the PRKAA gene leads to the upregulation of the catalytic subunit of AMPK, which serves as the main regulator of cellular response and is responsible for maintaining energy balance within the cell [132, 133]

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