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Basal insulin therapy should be considered when introducing dual or triple therapy and should be intensified adding a mealtime insulin or a GLP-1 RA when glycemic control needs to be optimized [1]

Think in terms of strategy, not transactions Each prescription shouldnt be a one-off decision

So far, studies on these new, multi-agonist drugs suggest that activating multiple receptors may lead to greater weight loss than GLP-1 alone

Single doses of SAR441255 up to 150 g were well tolerated and the most frequent treatment-emergent adverse events were gastrointestinal disorders, as is typical with these compounds

Add-on Combination Therapy with Pioglitazone A total of 353 patients with type 2 diabetes participated in a 24-week, randomized, double-blind, placebo-controlled study designed to assess the efficacy of JANUVIA in combination with pioglitazone