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Por ejemplo, a las 40 semanas de tratamiento, los pacientes tratados con retatrutida mostraron una mayor reduccin de HbA1c y peso que aquellos que recibieron placebo

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While GLP-1 is primarily synthesized and secreted by intestinal L-cells in response to nutrient intake, it is also produced in the brain, particularly in the nucleus of the solitary tract in the brainstem