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Mislocalized TDP-43 in neurons and glial cells disrupts RNA processing and proteostasis, leading to cellular dysfunction that contributes to pathological glial alterations and neurodegeneration

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doi: 10.1002/art.22085 159 GarciaRJFrancisLDawoodMLaiZWFaraoneSVPerlA

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12, 14, 17, 26 However, tissue carnitine levels in the heart, liver, and skeletal muscle are significantly lower than those in controls, even after L-carnitine administration