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Chronic cocaine exposure has been linked to an increased risk of Parkinsons disease, as it promotes -synuclein overexpression in dopamine neurons, causing resting tremors and neurotoxic damage (Mash et al., 2003)

Avoid exposing them to extreme temperatures or direct sunlight

Mechanisms of mitochondrial fission and fusion

It might be that the lower SOD activity of positive animals reflects excessive consumption of the enzyme (antioxidant consumption hypothesis) to buffer increased superoxide production rather than an inhibitory effect (antioxidant inhibition hypothesis) of viral infection on the enzyme 35

Dosing protocols vary widely across available studies, and long-term safety data, potential interactions, and optimal delivery methods remain poorly characterized in clinical populations