The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
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Since its isolation and characterisation in the early 1990s, it has become one of the most extensively studied peptides in regenerative biology research, with a broad research profile spanning gastrointestinal, musculoskeletal, vascular, and neurological tissue models
Outcome measures cover histological damage scoring, cytokine panels (TNF-, IL-6, IL-10), mucosal blood flow, tight junction protein expression by Western blot, and stool consistency scoring for colitis models
Metwaly HH, Fathy SA, Abdel Moneim MM, Emam MA, Soliman AF, El-Naggar ME, Omara EA, El-Bana MA (2022) Chitosan and solid lipid nanoparticles enhance the efficiency of alpha-lipoic acid against experimental neurotoxicity