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Globally, regardless of target specificity, the few antibodies validated from combinatorial libraries show lower purities, higher polydispersities and lower melting temperatures, T m , than the subset of validated antibodies from paired libraries, hinting at potentially poorer overall developability profiles for antibodies with random, non-cognate chain pairings

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Es kommt zu einem Glutathionmangel

[DOI] [PubMed] [Google Scholar] 53

2019 Glutathione is studied as the principal substrate of the GST detoxification system and the master buffer of intracellular redox state