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The defection of mitophagy will lead to the accumulation of dysfunctional mitochondria, resulting in the leakage of Cytc into the cytoplasm to induce the activation of the caspase signaling pathway, and contribute to cell death (Sinha et al., 2013

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Regular follow-up with healthcare professionals, including GPs, practice nurses, and dietitians, can provide ongoing support and ensure that any additional metabolic or hormonal issues are identified and addressed appropriately

Oral contraceptives tirzepatide slows gastric emptying, which may reduce the absorption and effectiveness of oral birth control pills