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4c, replacement of the first six residues of GLP-2 by those of GLP-1 (i.e., double mutant D 3P E and S 5P T) decreased cAMP accumulation by 12-fold compared to the native peptide, suggesting that subtle substitution may directly alter receptor activation

Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort

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