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Pooled 2020-2026 data (12 studies, n=892) report mild erythema (4.2%), pruritus (2.1%), no systemic copper overload (serum levels unchanged)

Hypoallergenic- can be used during pregnancy or breastfeeding period

Subsequently, OPN induces tumor cells to produce TGF- , which in turn upregulates PD-1 expression on immune cells and ultimately increases the sensitivity of breast cancer to PD-1 immunotherapy

Effect of exenatide on nonalcoholic steatohepatitis and inflammation-related indices in diabetic patients with non-alcoholic fatty liver disease

Some patients transition from two meals daily to one meal plus a small snack, or even one substantial meal with minimal additional eating