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Despite these recommendations, there is limited real-world data evaluating outcomes of GLP1-RAs specifically in patients with moderate to advanced CKD or ESRD

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Safety Winner: Semaglutide GLP-1 RAs in general have a lower side effect risk than tesamorelin, and the literature currently favors semaglutides safety profile over that of tirzepatide

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Statistical analysis Data were analysed using the GraphPad Prism version 7 (GraphPad Software) with the exception of the analysis of RNA-sequencing data, which is described in the Materials and Methods section under RNA-sequencing data analysis