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Tert-Butyl hydroperoxide (TBHP), 27-Dichlorodihydrofluorescein diacetate (DCFDA), dimethyl sulfoxide (DMSO) for molecular biology, N-acetyl-L-cysteine (NAC), Pluronic F127, paraquat dichloride dihydrate, tannic acid, ethylenediaminetetraacetic acid (EDTA), ascorbic acid/sodium-L-ascorbate, sodium hydroxide (NaOH), hydrochloric acid (HCl), Mayers hematoxylin, and Eosin Y alcoholic solution were purchased from Sigma Aldrich (St

While neuroinflammation is an innate mechanism designed to protect against infections and injuries, chronic or dysregulated neuroinflammation contributes to the development and progression of CNS disorders ranging from early developmental disorders such as autism spectrum disorders (ASD) (Han et al., 2021) and schizophrenia (Mller et al., 2015) to neurogenerative disorders (Zhang et al., 2023) including Alzheimers and Parkinsons disease (Gella and Durany, 2009

Consider these complementary elements: Selenium: This mineral is a necessary cofactor for the enzyme that allows glutathione to neutralize free radicals

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