Spore-based probiotics are encapsulated with a special layer that moves through the stomach and small intestine and into the large intestine (where they need to go!) without breaking down
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In addition, NRF2 also regulates the expression of ferritin subunits to promote free Fe 2+ sequestration, which can inhibit Fe 2+ -dependent free radical generation, and thus reducing the Fe 2+ -mediated toxicity [36]
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