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Electrical or pharmacological stimulation of this nucleus increases BAT thermogenesis (96101)
In a large retrospective cohort study including over 1.6 million patients with Type 2 Diabetes, with no prior diagnosis of obesity associated cancers, a significantly reduced risk in 10 out of 13 obesity associated cancers was reported with the use of GLP-1 agonists, including esophageal, colorectal, endometrial, gallbladder, kidney, liver, ovarian, pancreatic cancer, meningioma, and multiple myeloma 17
They work best as part of a comprehensive program that includes dietary modifications, exercise, and in many cases a primary weight loss medication such as semaglutide or tirzepatide