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In patients taking weak CYP2D6 inhibitors, endoxifen plasma concentrations were 24% lower than those not taking CYP2D6 inhibitors, but in those taking potent CYP2D6 inhibitors, endoxifen concentrations were 72% lower [8]

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Regarding the latter resolution, this paper introduced the use of GLP-1RAsa drug class traditionally used in the treatment and management of T2DM and obesityas a potential avenue for the treatment of neurodegenerative diseases and neuropathologic conditions alike due to the drugs extensively cited neuroprotective effects