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Friedman A et al (1996): Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response, Nat Med

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Because protein binding has rapid equilibration, the total amount of drug metabolised will be independent of protein binding but highly dependent on liver blood flow

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MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis