News Large-scale analysis of more than 400,000 Reddit posts has identified patient-reported symptoms associated with glucagon-like peptide-1 receptor agonists that may not be fully captured in clinical trials, with reproductive and temperature-related effects emerging as signals for further investigation in real world evidence A research team at the University of Pennsylvania, Philadelphia, USA, has used artificial intelligence to analyse more than 400,000 Reddit posts and identified patient-reported symptoms associated with glucagon-like peptide-1 (GLP-1) receptor agonists that may not have been explored in randomised clinical trials (RCTs) or regulatory documentation
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348 Similarly, in human chondrocytes stimulated by TNF, GLP-1 analogs (such as liraglutide) showed an anti-catabolic effect, reducing the mRNA expression of MMP-3, MMP-13, and ADAMTS5
CL Answer Bee pollen: Purported health benefits and possible side effects Bee pollen is promoted for numerous health conditions, including supporting immune health and boosting energy
Sufficient protein intake at least 1/2 gram per pound of body weight a day can help protect the body from bone and muscle mass loss