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Additionally, changes in the expression levels of genes that are associated with the significantly altered metabolites and their respective metabolic pathways were studied using RT-qPCR and correlated with alterations in the metabolite levels, followed by correlation to the survival of patients receiving tamoxifen using data obtained from Kaplan Meier webtool

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Both compounds bind the ghrelin receptor (formally the growth hormone secretagogue receptor type 1a) on the surface of pituitary somatotrophs and on neurons in the hypothalamus