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Anal Biochem 72: 248254

5-Amino-1MQ binds the NNMT active site at low micromolar Ki, producing selective inhibition relative to other SAM-dependent methyltransferases [1]

It has also been shown that neuronal tissue has a dense expression of both the GIPR and the GLP-1R [17]

These include colorectal cancer, bowel stricture (narrowing), abdominal tumor pressing on the colon, and any other cause of bowel obstruction (Basilisco 2013)