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The answer is that these approaches are often complementary rather than competitive
If your vial is 2.5 mg/mL, then 10 units equals 0.25 mg, which is the standard starting dose
Both approaches involve the attempt to remove malignant cells and spare normal tissues, though this remains difficult due to the heterogeneity of tumour s, intrinsic drug resistance and the ability of normal tissues to be affected adversely by anticancer treatments
Secondly, it has been indicated that high doses or long-term NAM reduces the methyl group availability and cellular methylation potential via promoting the methyl sink in the form of 1MNA
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