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17 The maintenance of iron homeostasis plays a key role in vital processes such as erythropoiesis, energy metabolism of muscle, cell cycle regulation, hormone production, immune system function, heme synthesis, DNA replication and repair, brain development and aging, and the formation of cytochromes

They found those who were on the GLP-1 medications were less than half as likely to die within five years compared to patients who were not taking the drugs (15.5% vs

The combination produces nausea as your digestive system adjusts to this new signaling pattern

So even though you can find GLP-1 in someone living with obesity, it's not signaling the brain enough to modify their appetite

Melanotan I appears to have a better safety profile than Melanotan II