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Shoulders on the main peak or unexpected peaks at 30-60% of the main peak retention time suggest truncated sequences (deletion products from failed couplings) that often retain partial activity and confound pharmacological interpretation

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119,129 These metalloregulatory proteins function as metal-dependent derepressors, 130,131 metal-dependent corepressors, 132134 and metal-dependent activators, 135 of transcription (Figure 6A)

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