CT388-103 was a multi-center, randomized, double-blind, placebo-controlled, parallel-group, dose-finding Phase II study conducted in 469 adults with obesity or who are overweight and have at least one weight-related comorbidity, excluding type 2 diabetes
Find it Here Digital Twin Care Platform supports sustained weight loss, shortens treatment, and lowers the total cost of care for employers and health plans Mountain View, CA May 21, 2026 - Twin Health, the first Digital Twin Care Platform for cardiometabolic health, today announced the launch of its GLP-1 Stewardship Model to reduce long-term dependence on GLP-1s
Healthcare providers may consider using standardized screening tools such as the PHQ-9 (Patient Health Questionnaire-9) to monitor for depression symptoms during follow-up visits, particularly for patients with pre-existing mental health conditions
Critically, the retatrutide data also showed that weight loss had not plateaued by the end of the trial period
Additionally, some patients experience an initial worsening of acne symptomsoften called the Accutane purgeas the medication begins to work
