Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohns disease
* Correspondence: Pietro Alifano, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Key research themes involving glutathione include: Scavenging of free radicals (e.g., peroxides, nitrogen dioxide, hypochlorous acid) Support of other antioxidant systems (e.g., vitamin C and vitamin E recycling) Detoxification via glutathione S-transferases and related enzymes Regulation of protein folding, disulfide-bond formation, and thiol redox status Modulation of inflammatory mediators, nitric oxide pathways, and cellular metabolism Because endogenous glutathione synthesis capacity appears to decrease with age in many models, glutathione is frequently used as both an experimental variable and a biomarker in studies of aging, disease susceptibility, and redox imbalance
doi: 2 10.12788/j.sder.12018.12056
Furthermore, preterm infants have a different gut microbial community than full-term infants