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In aging-related PD, the number of mitochondrial-lysosomal contacts decreases, and the instability of these contact sites leads to disruption of mitochondrial and lysosomal amino acid homeostasis

New research presented at the 2026 ASCO Gastrointestinal Cancers Symposium shows a reduced risk of colorectal cancer among GLP-1 users

Evaluation of N-glycosylation of secreted proteins N-glycosylation was evaluated by comparative WBs under basal conditions and after digestion with neuraminidase ((2 3, 6, 8, 9)) from Arthrobacter ureafaciens , Sigma-Aldrich), following the manufacturers instructions, and with N-glycosylase F (PNGase F, Sigma-Aldrich, Madrid, Spain)

Patients should be clearly informed of these limitations before considering either treatment

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