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Early recognition and intervention are crucial since some forms are treatable or reversible, while others benefit significantly from targeted therapies that slow functional decline

Beta cell death is coordinated through two convergent but distinct signaling cascades, including the intrinsic (mitochondrial) and extrinsic (death receptor) pathways [94]

Betroffen sind insbesondere das Hautorgan und das zentrale Nervensystem

The changes in the melanin index, moisture content of the stratum corneum, skin smoothness, skin elasticity and wrinkle formation were objectively assessed