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We needed to design a new molecule that could both get across the intestinal epithelium and would also be resistant to those peptidases [the DPP-4 enzyme] we talked about

Common contaminants are well tolerated in the assay, only 1-20 L of experimental sample is required

Gautier J-F, Choukem S-P, Girard J

Metformin carries a rare but serious risk called lactic acidosis, which becomes more concerning if kidney function declines

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