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The study concludes that DSIPs activating action on oxidative phosphorylation and its preventive effects under hypoxia provide a strong basis for understanding its previously reported stress-protective and antioxidant actions in vivo

Likewise, the suppressor oncogene p53 is capable of suppressing the activity of the IGF-1R promoter as well as lowering the endogenous levels of IGF-1R mRNA (Werner et al, 2000)

CD95-mediated apoptosis is impaired at receptor level by cellular FLICE-inhibitory protein (long form) in wild-type p53 human ovarian carcinoma

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