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The apolipoprotein E4 genotype contributes to the abnormal accumulation of lipid droplets (LD) in microglia and the formation of neurotoxic LD-accumulating microglia, which are capable of directly inducing neuronal Tau phosphorylation and apoptosis, and the degree of LD accumulation is positively correlated with the severity of cognitive decline and pathology [148]

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In most studies, mitogenetic effects were maximized in diffuse daylight, but were not observed in complete darkness or in bright daylight [1]

It is involved in the bodys natural detoxification pathways and helps support the neutralization of free radicals generated through normal metabolic processes