Any disruption of the normal function of the ER, especially oxidative stress, can lead to ER stress, which is characterised by an accumulation of misfolded or unfolded proteins in the ER lumen
NAC is highly valued in the wellness world because it is a stable form of cysteine that the body can easily use
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Validation at low concentration levels for analytes naturally present at high concentrations, such as Gln, Glu, and GSH, can be challenging, as the response from low-concentration SA may not differ significantly from the endogenous concentration, leading to inaccurate results
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