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This was evidenced by a decreased requirement for intensification of treatment associated with better preservation of glycemic control, as well as better sustained -cell function as reflected in the fasting HOMA-2 during the 2-year follow-up period

Despite substantial advances, critical gaps remain in understanding how ABASnRK2 signaling interfaces with ABA-independent regulatory pathways and how epigenetic mechanisms including DNA methylation, histone modifications, and miRNA-mediated regulation shape drought adaptation across developmental stages and environmental contexts

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Improper storage causes irreversible peptide degradation: temperatures above 30C denature protein structure within 2 hours, freezing reconstituted peptides creates ice crystals that aggregate peptide molecules, and storing lyophilised vials in humid environments introduces moisture that hydrolyzes peptide bonds even before reconstitution