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On one hand, ROS-mediated damage to the cystine-glutamate antiporter SLC7A11expressed on RMECs, RPE cells, and Mller cellsimpairs cystine-cysteine biotransformation, disrupts the GSH- GPX4 antioxidant axis, and thereby triggers ferroptosis in these cell populations

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SPSS 17.0.1 (SPSS Inc., Chicago, IL, USA) version was used for data analysis

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