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36 MET is an immune gene encoding hepatocyte growth factor (HGF), mutations in which induce disruption of multiple downstream targets in signalling cascades, resulting in critical functional deficits in brain development
For example, TLR2/TLR4 antagonists can reduce overactive inflammation in infected wounds, while topical TLR agonists can enhance pathogen recognition and immune activation in immunocompromised conditions [36]
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