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Additionally, the appetite-suppressing properties of GLP-1 agonists have made them a game-changer in obesity treatment, leading to approvals for weight management in drugs like Wegovy and Saxenda
T hermodynamic Integration and QM/MM calculations Structure preparations for thermodynamic integration The structure for BTK-Ibrutinib complex (PDB: 5P9J 93 ) was used as a starting structure to build the complexes of compound 12 (O) and 14 (S)
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